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Sophie Miller
Sophie Miller
Sophie Miller
Graduate Student
Email:
semiller@caltech.edu
I am improving and applying bioorthogonal noncanonical amino acid tagging (BONCAT) methods to enable time-resolved proteomic analysis of newly synthesized proteins in zebrafish larvae. I am also using BONCAT in primary cultures of rat cortical neurons to investigate changes in protein expression in response to treatment with low doses of ketamine with the goal of better understand the molecular underpinnings of its rapid-acting antidepressant effects.